Shere Khan from Rudyard Kipling's Jungle Book.
Even if Shere Khan is Hindi for "King Tiger", his original birth name, Lungri, could be translated as "The Lame One". If my memory serves me right, the great and menacing tiger was born with a crippled leg, which prevented him from hunting wild animals of the jungle, as they were too quick for him to catch. He started to prey upon villagers' cattle instead and eventually became a man-eater.
It seems that this disability of his is often overlooked, but I think it really adds a lot to this character and gives a reasonable explanation to his habits. Before I read the books I always thought Shere Khan ate humans and their domesticated animals simply because he was the villain of the story, now I know it's partially because he doesn't have a choice. It's actually quite tragic if you think about it.
Staedtler pigment liner and Gimp.