Bloodletting

Bloodletting (or blood-letting) is the withdrawal of often small quantities of blood from a patient to cure or prevent illness and disease. Bloodletting was based on an ancient system of medicine in which blood and other bodily fluid were regarded as "humors" that had to remain in proper balance to maintain health. It was the most common medical practice performed by physicians from antiquity until the late 19th century, a span of almost 2,000 years. The practice has now been abandoned for all except a few very specific conditions. It is conceivable that historically, in the absence of other treatments for hypertension, bloodletting could sometimes have had a beneficial effect in temporarily reducing blood pressure by reducing blood volume. However, since hypertension is very often asymptomatic and thus undiagnosable without modern methods, this effect was unintentional. In the overwhelming majority of cases, the historical use of bloodletting was harmful to patients.

-Wikipedia

16th century medicine sure was interesting...
Being an albino, a former runt of the litter and blessed with particularly poor immune system, Machete probably had to go though a variety of illnesses during his lifetime. At the point he was a cardinal he'd probably be able to afford a personal doctor who would be in charge of dealing with his changeable health and regular bleeding sessions.

No sir, he's not liking it.

Renaissance clothing and furniture? I don't even know. Usable references were at bay so I just improvised something that might fit the setting.
And the doctor is a Bracco Italiano, never drawn any dogs of that breed before. Rather striking looking canines.

Graphite and Gimp.

Characters and artwork ©GhoulShoe